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Hermann Haller Selected Research

Calcium Dobesilate

11/2021Calcium Dobesilate Modulates PKCδ-NADPH Oxidase- MAPK-NF-κB Signaling Pathway to Reduce CD14, TLR4, and MMP9 Expression during Monocyte-to-Macrophage Differentiation: Potential Therapeutic Implications for Atherosclerosis.
1/2020Calcium dobesilate reduces VEGF signaling by interfering with heparan sulfate binding site and protects from vascular complications in diabetic mice.
1/2017Molecular Mechanisms and Treatment Strategies in Diabetic Nephropathy: New Avenues for Calcium Dobesilate-Free Radical Scavenger and Growth Factor Inhibition.

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Hermann Haller Research Topics

Disease

53Inflammation (Inflammations)
05/2022 - 01/2002
36Hypertension (High Blood Pressure)
12/2021 - 12/2002
30Acute Kidney Injury (Acute Renal Failure)
05/2022 - 09/2002
30Fibrosis (Cirrhosis)
05/2022 - 11/2002
26Proteinuria
03/2019 - 07/2003
25Chronic Renal Insufficiency
05/2022 - 01/2002
23Albuminuria
01/2022 - 01/2002
21Sepsis (Septicemia)
12/2022 - 02/2004
21Infections
12/2021 - 01/2003
19Diabetic Nephropathies (Diabetic Nephropathy)
01/2022 - 08/2004
17Reperfusion Injury
11/2020 - 09/2002
15Type 2 Diabetes Mellitus (MODY)
01/2021 - 04/2005
14Ischemia
10/2020 - 09/2002
13Renal Insufficiency (Renal Failure)
01/2022 - 01/2002
13Critical Illness (Critically Ill)
09/2018 - 02/2004
12Atherosclerosis
05/2022 - 01/2002
10Cardiovascular Diseases (Cardiovascular Disease)
12/2021 - 05/2009
10Neoplasms (Cancer)
09/2018 - 03/2002
9Kidney Diseases (Kidney Disease)
12/2021 - 09/2003
8Edema (Dropsy)
12/2021 - 01/2016
8Vascular Remodeling
02/2016 - 01/2002
7Septic Shock (Toxic Shock Syndrome)
12/2022 - 10/2018
7Heart Failure
08/2020 - 10/2004
7Anti-Neutrophil Cytoplasmic Antibody-Associated Vasculitis
11/2015 - 01/2003
6Necrosis
01/2022 - 09/2002
6Diabetes Mellitus
12/2021 - 11/2004
6Vasculitis (Vasculitides)
06/2021 - 01/2001
6Disease Progression
10/2020 - 08/2005
6Delayed Graft Function
01/2018 - 08/2004
6Hypertrophy
11/2014 - 06/2003
6Essential Hypertension
03/2010 - 04/2003
5Body Weight (Weight, Body)
01/2022 - 04/2008
5Urinary Tract Infections (Urinary Tract Infection)
10/2019 - 10/2005
5Chronic Kidney Failure (Chronic Renal Failure)
06/2013 - 02/2002
4Nephrotic Syndrome (Syndrome, Nephrotic)
01/2022 - 11/2016
4Hypoxia (Hypoxemia)
12/2021 - 01/2008
4Glomerulonephritis
06/2021 - 01/2003
4Endotoxemia
01/2021 - 01/2009
4Peritonitis
05/2019 - 08/2005
4Seizures (Absence Seizure)
01/2017 - 01/2012
4Hemolytic-Uremic Syndrome
01/2017 - 04/2013
4Vascular System Injuries
07/2009 - 02/2002

Drug/Important Bio-Agent (IBA)

19CytokinesIBA
12/2021 - 02/2007
19Proteins (Proteins, Gene)FDA Link
12/2021 - 07/2003
18Angiopoietin-2IBA
12/2021 - 01/2008
16Biomarkers (Surrogate Marker)IBA
01/2022 - 01/2002
14CreatinineIBA
11/2020 - 01/2002
11Pharmaceutical PreparationsIBA
11/2021 - 01/2009
11Glucose (Dextrose)FDA LinkGeneric
01/2021 - 07/2003
10Urokinase-Type Plasminogen Activator (Urokinase)FDA Link
11/2017 - 01/2002
9Antihypertensive Agents (Antihypertensives)IBA
12/2021 - 07/2008
9AlbuminsIBA
11/2020 - 11/2004
9olmesartanIBA
12/2017 - 08/2004
9Angiotensin Receptor AntagonistsIBA
09/2015 - 04/2005
9Protein Kinase CIBA
04/2013 - 04/2002
7LigandsIBA
12/2021 - 01/2008
7Vascular Endothelial Growth Factor A (Vascular Endothelial Growth Factor)IBA
01/2020 - 03/2003
7Peptides (Polypeptides)IBA
11/2019 - 09/2003
7Angiotensin IIIBA
08/2015 - 01/2002
7OsteopontinIBA
08/2015 - 03/2010
7Protein Isoforms (Isoforms)IBA
04/2013 - 08/2004
7Hydroxymethylglutaryl-CoA Reductase Inhibitors (HMG-CoA Reductase Inhibitors)IBA
03/2010 - 03/2002
6ChemokinesIBA
05/2022 - 03/2009
6EnalaprilFDA LinkGeneric
10/2020 - 01/2006
6lercanidipineIBA
01/2016 - 01/2006
6Urokinase Plasminogen Activator ReceptorsIBA
01/2016 - 03/2002
6Antineutrophil Cytoplasmic Antibodies (ANCA)IBA
07/2010 - 01/2001
5Norepinephrine (Noradrenaline)FDA LinkGeneric
12/2022 - 10/2018
5CollagenIBA
01/2022 - 02/2007
5Immunoglobulin G (IgG)IBA
12/2021 - 09/2005
5MicroRNAs (MicroRNA)IBA
01/2021 - 05/2011
5finerenoneIBA
01/2021 - 01/2014
5Interleukin-6 (Interleukin 6)IBA
01/2019 - 08/2004
5Shiga Toxin (Shigella Toxin)IBA
01/2017 - 07/2012
5C-Reactive ProteinIBA
05/2012 - 08/2004
5Angiopoietin-1IBA
05/2012 - 01/2008
5Tumor Necrosis Factor-alpha (Tumor Necrosis Factor)IBA
11/2009 - 08/2004
5NF-kappa B (NF-kB)IBA
02/2004 - 01/2002
4NADPH Oxidases (NAD(P)H oxidase)IBA
11/2021 - 04/2003
4Mineralocorticoid Receptor AntagonistsIBA
01/2021 - 01/2014
4Interleukin-17 (Interleukin 17)IBA
01/2021 - 09/2013
4Transforming Growth Factors (Transforming Growth Factor)IBA
11/2020 - 09/2003
4Streptozocin (Streptozotocin)FDA Link
01/2020 - 08/2004
4Anti-Bacterial Agents (Antibiotics)IBA
01/2018 - 07/2004
4Rituximab (Mabthera)FDA Link
12/2017 - 01/2009
4nephrinIBA
12/2016 - 02/2007
4Oxidoreductases (Dehydrogenase)IBA
07/2015 - 02/2002
4TIE-2 Receptor (Receptor, TIE 2)IBA
05/2012 - 01/2008
4Fibronectins (Fibronectin)IBA
08/2009 - 11/2004
4N,N-dimethylarginine (asymmetric dimethylarginine)IBA
04/2009 - 01/2002
4Nitric Oxide Synthase (NO Synthase)IBA
08/2005 - 01/2002

Therapy/Procedure

54Therapeutics
12/2022 - 02/2002
27Kidney Transplantation
01/2022 - 03/2004
17Transplantation
07/2021 - 07/2003
10Renal Replacement Therapy (Therapies, Renal Replacement)
09/2018 - 08/2004
7Plasma Exchange
12/2022 - 11/2010
7Peritoneal Dialysis
11/2020 - 08/2005
6Ligation
01/2020 - 01/2011
6Renal Dialysis (Hemodialysis)
05/2019 - 07/2010
5Punctures
01/2020 - 01/2011